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Genetics

Antisense Therapy Explained: How Blocking mRNA Can Treat Genetic Disorders

Antisense therapy has proven to be effective at treating previously untreated genetic disorders including Duchenne muscular dystrophy and familial hypercholesterolemia. The therapy has also demonstrated promising results in Phase III clinical trials for amyotrophic lateral sclerosis (ALS). What is antisense therapy, and how are antisense oligonucleotides used to treat genetic disorders? Background Genetic Disorders and […]

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Commentary Genetics

Dog Behavior Unrelated to Breed? Researchers Respond to Controversy, Misleading Media Coverage

Introduction A recent dog genomics study from UMass Chan School of Medicine researchers claims to challenge popular breed stereotypes, concluding that dog breed is a poor predictor of individual behavior. According to the study, which was the feature article in the April 29 issue of Science, just 9% of variation in dog behavior can be […]